| Name | What | Region | Country | Lat | Long | Elev ft. | Pop est |
|---|---|---|---|---|---|---|---|
| Sabana Grande | city | Managua | Nicaragua | 12.12 | -86.17 | 272 | 261875 |
| Salamina | city | Managua | Nicaragua | 11.99 | -86.65 | 22 | 3879 |
| Salto | city | Managua | Nicaragua | 11.87 | -86.41 | 830 | 26586 |
| Samaria | city | Managua | Nicaragua | 11.99 | -86.54 | 219 | 5513 |
| San Andres | city | Managua | Nicaragua | 12.17 | -86.40 | 830 | 80156 |
| San Antonio | city | Managua | Nicaragua | 12.35 | -86.14 | 147 | 1840 |
| San Antonio | city | Managua | Nicaragua | 12.05 | -86.27 | 1820 | 306903 |
| San Antonio | city | Managua | Nicaragua | 12.47 | -86.04 | 830 | 2962 |
| San Antonio | city | Managua | Nicaragua | 12.32 | -86.17 | 134 | 1257 |
| San Bartolo | city | Managua | Nicaragua | 11.92 | -86.55 | 229 | 7054 |
| San Benito | city | Managua | Nicaragua | 12.32 | -86.07 | 242 | 13205 |
| San Benito | city | Managua | Nicaragua | 12.57 | -86.28 | 830 | 2089 |
| San Blas | city | Managua | Nicaragua | 12.48 | -86.05 | 830 | 2948 |
| San Cayetano | city | Managua | Nicaragua | 11.90 | -86.52 | 830 | 8795 |
| San Coyotano | city | Managua | Nicaragua | 11.90 | -86.52 | 830 | 8795 |
| San Cristóbal | city | Managua | Nicaragua | 12.15 | -86.15 | 193 | 132434 |
| San Emilio | city | Managua | Nicaragua | 12.31 | -86.03 | 282 | 11318 |
| San Ernesto | city | Managua | Nicaragua | 12.08 | -86.28 | 1187 | 374950 |
| San Francisco | city | Managua | Nicaragua | 12.17 | -86.35 | 298 | 153582 |
| San Francisco | city | Managua | Nicaragua | 12.50 | -86.30 | 111 | 1603 |
| San Francisco | city | Managua | Nicaragua | 12.24 | -85.98 | 236 | 4322 |
| San Francisco | city | Managua | Nicaragua | 12.04 | -86.28 | 2509 | 235661 |
| San Francisco Libre | city | Managua | Nicaragua | 12.50 | -86.30 | 111 | 1603 |
| San Francisco del Carnerico | city | Managua | Nicaragua | 12.50 | -86.30 | 111 | 1603 |
| San Francisco del Carnicero | city | Managua | Nicaragua | 12.50 | -86.30 | 111 | 1603 |
| San Francisco del Peñón | city | Managua | Nicaragua | 12.41 | -86.04 | 328 | 2980 |
| San Gregorio | city | Managua | Nicaragua | 12.38 | -86.05 | 282 | 2997 |
| San Ildefonso | city | Managua | Nicaragua | 12.26 | -86.08 | 232 | 34287 |
| San Isidro | city | Managua | Nicaragua | 12.21 | -86.30 | 127 | 11699 |
| San Isidro de la Cruz Verde | city | Managua | Nicaragua | 12.09 | -86.26 | 964 | 390439 |
| San Jacinto | city | Managua | Nicaragua | 12.34 | -86.02 | 830 | 6522 |
| San Jorge | city | Managua | Nicaragua | 12.02 | -86.22 | 1046 | 152772 |
| San Jorge | city | Managua | Nicaragua | 12.53 | -86.23 | 830 | 2086 |
| San Jose | city | Managua | Nicaragua | 12.00 | -86.55 | 213 | 5513 |
| San Jose del Cardon | city | Managua | Nicaragua | 12.00 | -86.32 | 2831 | 71364 |
| San José | city | Managua | Nicaragua | 12.35 | -86.22 | 167 | 1192 |
| San José | city | Managua | Nicaragua | 12.10 | -86.32 | 882 | 401242 |
| San Juan | city | Managua | Nicaragua | 12.17 | -86.03 | 144 | 31925 |
| San Juan | city | Managua | Nicaragua | 11.92 | -86.62 | 29 | 3008 |
| San Lorenzo | city | Managua | Nicaragua | 12.12 | -86.57 | 288 | 3872 |
| San Lorenzo | city | Managua | Nicaragua | 11.81 | -86.45 | 259 | 16324 |
| San Luis | city | Managua | Nicaragua | 12.18 | -86.37 | 255 | 105409 |
| San Luis | city | Managua | Nicaragua | 12.48 | -86.28 | 131 | 1394 |
| San Luis | city | Managua | Nicaragua | 11.89 | -86.58 | 45 | 4596 |
| San Martin | city | Managua | Nicaragua | 12.18 | -86.04 | 141 | 32764 |
| San Miguel | city | Managua | Nicaragua | 12.15 | -86.22 | 272 | 212195 |
| San Pablo | city | Managua | Nicaragua | 11.84 | -86.41 | 830 | 26351 |
| San Patricio | city | Managua | Nicaragua | 12.11 | -86.31 | 830 | 387213 |
| San Pedro | city | Managua | Nicaragua | 11.79 | -86.47 | 124 | 10009 |
| San Rafael | city | Managua | Nicaragua | 11.85 | -86.44 | 403 | 25529 |
| San Rafael | city | Managua | Nicaragua | 12.35 | -86.22 | 164 | 1119 |
| San Rafael del Sur | city | Managua | Nicaragua | 11.85 | -86.44 | 403 | 25529 |
| San Rafaelito | city | Managua | Nicaragua | 12.05 | -86.57 | 190 | 5479 |
| San Ramon | city | Managua | Nicaragua | 11.96 | -86.31 | 2709 | 24608 |
| San Ramón | city | Managua | Nicaragua | 12.34 | -86.21 | 157 | 1223 |
| San Roque | city | Managua | Nicaragua | 12.45 | -86.21 | 183 | 2085 |
| San Sebastián | city | Managua | Nicaragua | 11.91 | -86.37 | 1243 | 22716 |
| San Vicente | city | Managua | Nicaragua | 12.02 | -86.28 | 2765 | 131030 |
| Santa Ana | city | Managua | Nicaragua | 11.98 | -86.38 | 1669 | 28829 |
| Santa Ana | city | Managua | Nicaragua | 12.10 | -86.35 | 944 | 340858 |
| Santa Bethania | city | Managua | Nicaragua | 12.08 | -86.37 | 1669 | 216975 |
| Santa Cruz | city | Managua | Nicaragua | 11.98 | -86.58 | 141 | 5500 |
| Santa Elena | city | Managua | Nicaragua | 11.91 | -86.49 | 830 | 10295 |
| Santa Elena | city | Managua | Nicaragua | 12.15 | -86.16 | 193 | 146714 |
| Santa Elisa | city | Managua | Nicaragua | 12.17 | -86.03 | 144 | 26252 |
| Santa Fe | city | Managua | Nicaragua | 12.22 | -86.03 | 196 | 27601 |
| Santa Gertrudis | city | Managua | Nicaragua | 12.29 | -86.19 | 131 | 620 |
| Santa Graciela | city | Managua | Nicaragua | 12.46 | -86.27 | 127 | 1344 |
| Santa Isabel | city | Managua | Nicaragua | 11.97 | -86.28 | 2575 | 19828 |
| Santa Isabel | city | Managua | Nicaragua | 11.95 | -86.38 | 1669 | 26646 |
| Santa Lucía | city | Managua | Nicaragua | 12.28 | -86.09 | 209 | 24065 |
| Santa Luisa | city | Managua | Nicaragua | 12.15 | -86.42 | 1669 | 47341 |
| Santa Maria | city | Managua | Nicaragua | 12.27 | -86.05 | 285 | 28583 |
| Santa Maria | city | Managua | Nicaragua | 12.56 | -86.34 | 160 | 2429 |
| Santa Rita | city | Managua | Nicaragua | 12.06 | -86.33 | 1669 | 296960 |
| Santa Rita | city | Managua | Nicaragua | 12.38 | -86.18 | 236 | 2059 |
| Santa Rita | city | Managua | Nicaragua | 12.06 | -86.50 | 403 | 5513 |
| Santa Rita de Plata | city | Managua | Nicaragua | 12.27 | -86.48 | 334 | 2579 |
| Santa Rosa | city | Managua | Nicaragua | 12.08 | -86.30 | 1669 | 380006 |
| Santa Rosa | city | Managua | Nicaragua | 12.12 | -86.20 | 830 | 332326 |
| Santa Tecla | city | Managua | Nicaragua | 12.04 | -86.31 | 1876 | 246749 |
| Santa Teresa | city | Managua | Nicaragua | 11.89 | -86.43 | 830 | 22865 |
| Santa Teresa | city | Managua | Nicaragua | 12.47 | -86.16 | 377 | 2342 |
| Santiago | city | Managua | Nicaragua | 11.96 | -86.33 | 2509 | 28676 |
| Santiago | city | Managua | Nicaragua | 12.15 | -86.52 | 830 | 3726 |
| Santo Domingo | city | Managua | Nicaragua | 12.08 | -86.25 | 1043 | 379559 |
| Santo Domingo | city | Managua | Nicaragua | 11.87 | -86.46 | 377 | 20353 |
| Santo Domingo de Guzmán | city | Managua | Nicaragua | 12.08 | -86.25 | 1043 | 379559 |
| Sitalapa | city | Managua | Nicaragua | 11.92 | -86.47 | 830 | 9508 |
| Sitio Itastalia | city | Managua | Nicaragua | 11.95 | -86.55 | 249 | 6248 |
| Sitios Loma Alegre | city | Managua | Nicaragua | 11.78 | -86.47 | 124 | 8729 |
| Soledad | city | Managua | Nicaragua | 12.04 | -86.64 | 68 | 4900 |