| Name | What | Region | Country | Lat | Long | Elev ft. | Pop est |
|---|---|---|---|---|---|---|---|
| Isaac | city | Lunda Sul | Angola | -10.94 | 20.21 | 4189 | 298 |
| Isaac | city | Aquitaine | France | 44.61 | 0.37 | 249 | 6605 |
| Isaac | city | Margibi | Liberia | 6.60 | -9.98 | 830 | 7443 |
| Isaac | city | Dowa | Malawi | -13.37 | 33.68 | 4189 | 17346 |
| Isaac | city | Dowa | Malawi | -13.32 | 33.67 | 3759 | 14798 |
| Isaac | city | Muchinga | Zambia | -10.10 | 32.78 | 5029 | 1788 |
| Isaac | city | Northern | Zambia | -8.77 | 30.78 | 5236 | 1639 |
| Isaac | city | Virginia | United States | 36.69 | -76.97 | 65 | |
| Isaac Arriaga | city | Mexico | Mexico | 20.25 | -101.50 | 5869 | 8964 |
| Isaac Farm | city | Lofa | Liberia | 8.13 | -9.64 | 1669 | 1607 |
| Isaac Greavesbli | city | Grand Bassa | Liberia | 6.25 | -10.27 | 830 | 6925 |
| Isaac Mkunda | city | Muchinga | Zambia | -10.27 | 32.53 | 5029 | 1408 |
| Isaac Mukuntha | city | Malawi | -11.85 | 33.71 | 5029 | 5657 | |
| Isaac Mwanda | city | Eastern | Zambia | -13.12 | 32.13 | 2552 | 3576 |
| Isaac Njovu | city | Eastern | Zambia | -13.23 | 31.82 | 2073 | 3576 |
| Isaac Peral | city | Melilla | Spain | 35.29 | -2.95 | 3 | 97072 |
| Isaac Portilho | city | Goias | Brazil | -16.78 | -51.70 | 2011 | 13 |
| Isaac Town | city | Margibi | Liberia | 6.60 | -9.98 | 830 | 7443 |
| Isaacgbene | city | Bayelsa | Nigeria | 4.83 | 5.61 | 334 | 13814 |
| Isaacs | city | Valle del Cauca | Colombia | 3.57 | -76.49 | 2509 | 69030 |
| Isaacs Colonia | city | Texas | United States | 26.26 | -98.09 | 82 | |
| Isaacs Corner | city | Rhode Island | United States | 41.16 | -71.58 | 98 | |
| Isaacs Harbour | city | Nova Scotia | Canada | 45.18 | -61.67 | 85 | 199 |
| Isaacs Kolk | city | Northern Cape | South Africa | -30.35 | 21.49 | 3349 | 0 |
| Isaacs Kolk | city | Northern Cape | South Africa | -30.35 | 21.52 | 3349 | 0 |
| Isaacs Kraal | city | Northern Cape | South Africa | -31.00 | 19.37 | 3349 | 19 |
| Isaadene | city | Tanger-Tetouan | Morocco | 35.20 | -4.90 | 2509 | 7907 |
| Isaaga | city | Elazig Ili | Turkey | 38.83 | 40.14 | 6158 | 2831 |
| Isaagamezreasi | city | Elazig Ili | Turkey | 38.83 | 40.14 | 6158 | 2831 |
| Isaak | city | Ida-Virumaa | Estonia | 59.10 | 27.31 | 173 | 444 |
| Isaakio | city | Anatoliki Makedonia kai Thraki | Greece | 41.36 | 26.54 | 118 | 73551 |
| Isaakovka | city | Amurskaya Oblast' | Russia | 49.93 | 129.75 | 830 | 149 |
| Isaaks Draai | city | Northern Cape | South Africa | -30.21 | 24.03 | 4189 | 0 |
| Isaaksbrunn | city | //Karas | Namibia | -26.67 | 17.23 | 3349 | 0 |
| Isaakyan | city | Armenia | 40.62 | 43.73 | 5101 | 4827 | |
| Isaalani | city | Balikesir | Turkey | 39.71 | 28.31 | 1669 | 3428 |
| Isaaq | city | Jubbada Hoose | Somalia | 0.22 | 42.77 | 36 | 6109 |
| Isaaq Jilible | city | Jubbada Dhexe | Somalia | 1.90 | 41.63 | 830 | 1243 |
| Isaar | city | Bayern | Germany | 50.22 | 11.87 | 1745 | 6125 |
| Isaar | city | Wisconsin | United States | 44.57 | -88.28 | 830 | |
| Isaayedene Sidi Ahmed | city | Marrakech-Tensift-Al Haouz | Morocco | 31.20 | -9.80 | 830 | 6129 |