| Name | What | Region | Country | Lat | Long | Elev ft. | Pop est |
|---|---|---|---|---|---|---|---|
| Seal Mathis | city | Tennessee | United States | 36.51 | -83.26 | 1200 | |
| Seals (historical) | city | Tennessee | United States | 35.74 | -85.18 | 1794 | |
| Seaton | city | Tennessee | United States | 35.73 | -83.87 | 1046 | |
| Seaton Spring | city | Tennessee | United States | 35.81 | -83.50 | 1722 | |
| Seaton Subdivision | city | Tennessee | United States | 36.33 | -82.38 | 1742 | |
| Sebowisha | city | Tennessee | United States | 36.14 | -85.87 | 830 | |
| Seeber Flats | city | Tennessee | United States | 36.17 | -84.22 | 1236 | |
| Selby (historical) | city | Tennessee | United States | 36.23 | -85.48 | 1112 | |
| Selkirk (historical) | city | Tennessee | United States | 35.90 | -84.35 | 830 | |
| Selmer | city | Tennessee | United States | 35.17 | -88.59 | 830 | |
| Seminole Subdivision | city | Tennessee | United States | 35.86 | -85.08 | 1840 | |
| Seminole Woods | city | Tennessee | United States | 36.29 | -82.38 | 1899 | |
| Sengtown | city | Tennessee | United States | 36.61 | -86.44 | 866 | |
| Sentertown | city | Tennessee | United States | 36.05 | -83.83 | 1030 | |
| Sentinel Heights | city | Tennessee | United States | 35.50 | -85.00 | 830 | |
| Sequatchie | city | Tennessee | United States | 35.12 | -85.59 | 830 | |
| Sequatchie College | city | Tennessee | United States | 35.51 | -85.29 | 1000 | |
| Sequoia Grove | city | Tennessee | United States | 35.21 | -84.85 | 830 | |
| Sequoia Hills | city | Tennessee | United States | 36.10 | -82.87 | 1669 | |
| Sequooyah Estates | city | Tennessee | United States | 36.16 | -83.28 | 1669 | |
| Sequoyah Estates | city | Tennessee | United States | 35.51 | -84.38 | 941 | |
| Sequoyah Heights | city | Tennessee | United States | 35.77 | -84.17 | 912 | |
| Sequoyah Heights | city | Tennessee | United States | 36.37 | -82.40 | 1669 | |
| Sequoyah Hills | city | Tennessee | United States | 35.20 | -85.15 | 830 | |
| Sequoyah Hills | city | Tennessee | United States | 35.94 | -83.97 | 882 | |
| Sequoyah Shores | city | Tennessee | United States | 35.85 | -84.53 | 830 | |
| Serles | city | Tennessee | United States | 35.17 | -88.84 | 331 | |
| Servilla | city | Tennessee | United States | 35.24 | -84.46 | 1102 | |
| Seth | city | Tennessee | United States | 35.55 | -87.29 | 898 | |
| Settlers Knob | city | Tennessee | United States | 36.20 | -86.53 | 830 | |
| Settlers Point | city | Tennessee | United States | 35.95 | -86.95 | 830 | |
| Seven (historical) | city | Tennessee | United States | 35.27 | -87.24 | 898 | |
| Seven Cedars | city | Tennessee | United States | 35.35 | -84.53 | 889 | |
| Seven Islands | city | Tennessee | United States | 35.95 | -83.70 | 869 | |
| Seven Oaks | city | Tennessee | United States | 36.56 | -82.65 | 1669 | |
| Seven Oaks | city | Tennessee | United States | 36.19 | -83.40 | 1669 | |
| Sevenmile Hill | city | Tennessee | United States | 35.41 | -86.24 | 1059 | |
| Sevenoaks | city | Tennessee | United States | 35.91 | -84.09 | 1026 | |
| Seventeen Seventysix Estates | city | Tennessee | United States | 36.09 | -86.95 | 830 | |
| Seventy-Six Estates | city | Tennessee | United States | 36.52 | -87.26 | 830 | |
| Sevier Heights | city | Tennessee | United States | 35.77 | -83.94 | 1000 | |
| Sevier Home | city | Tennessee | United States | 35.90 | -83.87 | 898 | |
| Sevier Terrace | city | Tennessee | United States | 36.56 | -82.57 | 1669 | |
| Sevierville | city | Tennessee | United States | 35.87 | -83.56 | 908 | |
| Sewanee | city | Tennessee | United States | 35.20 | -85.92 | 1899 | |
| Sewee | city | Tennessee | United States | 35.59 | -84.68 | 830 | |
| Sexton | city | Tennessee | United States | 35.04 | -87.20 | 830 | |
| Seymour | city | Tennessee | United States | 35.89 | -83.72 | 980 | |
| Seymour Heights | city | Tennessee | United States | 35.88 | -83.76 | 1099 |