| Name | What | Region | Country | Lat | Long | Elev ft. | Pop est |
|---|---|---|---|---|---|---|---|
| MacArthurs Junction | city | South Carolina | United States | 34.42 | -82.28 | 830 | |
| Macbeth | city | South Carolina | United States | 33.27 | -79.97 | 65 | |
| Macedon | city | South Carolina | United States | 33.82 | -81.21 | 830 | |
| Macedonia | city | South Carolina | United States | 35.07 | -81.76 | 938 | |
| Macedonia | city | South Carolina | United States | 34.11 | -81.44 | 400 | |
| Mackay Subdivision | city | South Carolina | United States | 33.52 | -80.82 | 206 | |
| Maddens | city | South Carolina | United States | 34.46 | -82.05 | 830 | |
| Madeline | city | South Carolina | United States | 34.64 | -79.77 | 150 | |
| Madison | city | South Carolina | United States | 33.56 | -81.81 | 226 | |
| Madison | city | South Carolina | United States | 34.63 | -83.21 | 830 | |
| Magnolia Acres | city | South Carolina | United States | 34.78 | -82.37 | 905 | |
| Magnolia Bluff | city | South Carolina | United States | 32.38 | -80.73 | 3 | |
| Magnolia Place | city | South Carolina | United States | 34.22 | -82.05 | 830 | |
| Magnolia Ranch | city | South Carolina | United States | 32.83 | -80.05 | 9 | |
| Malibu | city | South Carolina | United States | 34.19 | -79.71 | 114 | |
| Mallard Bay | city | South Carolina | United States | 34.03 | -81.38 | 374 | |
| Mallory | city | South Carolina | United States | 34.39 | -79.51 | 98 | |
| Malta | city | South Carolina | United States | 33.88 | -80.58 | 88 | |
| Mandel Hall | city | South Carolina | United States | 34.07 | -81.11 | 232 | |
| Mandel Park | city | South Carolina | United States | 34.06 | -81.12 | 272 | |
| Mangums (historical) | city | South Carolina | United States | 34.76 | -80.34 | 830 | |
| Manning | city | South Carolina | United States | 33.70 | -80.21 | 85 | |
| Manning Acres | city | South Carolina | United States | 34.92 | -82.19 | 905 | |
| Manning Crossroads | city | South Carolina | United States | 34.47 | -79.46 | 124 | |
| Mansfield Park | city | South Carolina | United States | 34.85 | -82.45 | 1013 | |
| Manville | city | South Carolina | United States | 34.15 | -80.30 | 190 | |
| Maple | city | South Carolina | United States | 34.93 | -82.24 | 928 | |
| Maple Crossroads | city | South Carolina | United States | 33.91 | -79.01 | 26 | |
| Maple Ridge | city | South Carolina | United States | 32.99 | -80.02 | 26 | |
| Maplewood | city | South Carolina | United States | 34.92 | -82.21 | 902 | |
| Maplewood | city | South Carolina | United States | 35.10 | -81.62 | 830 | |
| Marden Ranchettes | city | South Carolina | United States | 33.96 | -80.50 | 285 | |
| Marietta | city | South Carolina | United States | 35.02 | -82.50 | 987 | |
| Marigold Heights | city | South Carolina | United States | 33.91 | -80.36 | 147 | |
| Marilyn Acres | city | South Carolina | United States | 34.55 | -82.61 | 830 | |
| Mariners Watch | city | South Carolina | United States | 32.38 | -80.69 | 6 | |
| Marion | city | South Carolina | United States | 34.18 | -79.40 | 75 | |
| Mark Island | city | South Carolina | United States | 32.47 | -80.67 | 3 | |
| Marlboro | city | South Carolina | United States | 34.54 | -79.73 | 85 | |
| Marlborough | city | South Carolina | United States | 32.76 | -79.98 | 13 | |
| Marlin Estates | city | South Carolina | United States | 32.99 | -80.20 | 52 | |
| Mars Bluff | city | South Carolina | United States | 34.21 | -79.66 | 78 | |
| Marsh Cove | city | South Carolina | United States | 32.82 | -80.03 | 9 | |
| Marsh Harbor | city | South Carolina | United States | 32.45 | -80.66 | 9 | |
| Marsh Hawk | city | South Carolina | United States | 32.48 | -80.64 | 19 | |
| Marsh Point | city | South Carolina | United States | 32.74 | -79.92 | 3 | |
| Marshall Forest | city | South Carolina | United States | 34.81 | -82.37 | 898 | |
| Marshall Heights | city | South Carolina | United States | 34.84 | -82.61 | 1112 | |
| Marshall Heights | city | South Carolina | United States | 33.52 | -80.86 | 275 | |
| Martha Law Estates | city | South Carolina | United States | 33.86 | -79.73 | 68 | |
| Martin | city | South Carolina | United States | 33.07 | -81.48 | 200 | |
| Martin Corner | city | South Carolina | United States | 33.41 | -79.71 | 49 | |
| Martin Crossroads | city | South Carolina | United States | 34.63 | -82.03 | 830 | |
| Martin Subdivision | city | South Carolina | United States | 33.88 | -80.35 | 127 | |
| Martindale | city | South Carolina | United States | 34.65 | -82.90 | 830 | |
| Martins Crossroads | city | South Carolina | United States | 33.70 | -79.96 | 75 | |
| Martins Landing | city | South Carolina | United States | 32.84 | -80.39 | 22 | |
| Martins Landing | city | South Carolina | United States | 32.65 | -81.39 | 39 | |
| Martins Point Landing | city | South Carolina | United States | 32.90 | -79.84 | 3 | |
| Martintowne | city | South Carolina | United States | 33.52 | -81.97 | 278 | |
| Mary | city | South Carolina | United States | 33.87 | -79.11 | 39 | |
| Marydell (historical) | city | South Carolina | United States | 35.05 | -82.43 | 1072 | |
| Marysville | city | South Carolina | United States | 33.43 | -79.15 | 16 | |
| Maryville | city | South Carolina | United States | 32.79 | -80.00 | 9 | |
| Maryville | city | South Carolina | United States | 33.34 | -79.30 | 16 | |
| Maryville | city | South Carolina | United States | 34.92 | -81.76 | 830 | |
| Mas Old Field Landing | city | South Carolina | United States | 33.05 | -80.45 | 36 | |
| Mascot | city | South Carolina | United States | 35.07 | -82.13 | 1000 | |
| Mason Estates | city | South Carolina | United States | 35.05 | -81.96 | 885 | |
| Masons Cross Road | city | South Carolina | United States | 34.56 | -82.78 | 830 | |
| Matassee (historical) | city | South Carolina | United States | 33.40 | -79.87 | 36 | |
| Mathais Crossroads | city | South Carolina | United States | 33.89 | -81.87 | 830 | |
| Mathews Heights | city | South Carolina | United States | 34.14 | -82.13 | 830 | |
| Mathews Village | city | South Carolina | United States | 34.17 | -82.15 | 830 | |
| Mathis (historical) | city | South Carolina | United States | 33.08 | -81.33 | 249 | |
| Mathis Corner | city | South Carolina | United States | 34.09 | -79.70 | 88 | |
| Matthews Estates | city | South Carolina | United States | 34.97 | -81.03 | 830 | |
| Maud | city | South Carolina | United States | 35.15 | -81.74 | 935 | |
| Mauldin | city | South Carolina | United States | 34.78 | -82.31 | 905 | |
| May Hilltop | city | South Carolina | United States | 34.32 | -79.22 | 88 | |
| Maybinton | city | South Carolina | United States | 34.45 | -81.48 | 410 | |
| Mayesville | city | South Carolina | United States | 33.99 | -80.21 | 134 | |
| Mayesville East Subdivision | city | South Carolina | United States | 33.98 | -80.20 | 134 | |
| Mayfair | city | South Carolina | United States | 34.17 | -79.81 | 118 | |
| Mayfield (historical) | city | South Carolina | United States | 35.02 | -82.57 | 944 | |
| Mayfield Acres | city | South Carolina | United States | 34.22 | -80.68 | 232 | |
| Maynards | city | South Carolina | United States | 34.77 | -80.27 | 830 | |
| Mayo | city | South Carolina | United States | 35.08 | -81.86 | 830 | |
| Mayo Heights | city | South Carolina | United States | 34.29 | -79.87 | 180 | |
| Mayo Mills | city | South Carolina | United States | 35.09 | -81.85 | 830 | |
| Mayson Crossroads | city | South Carolina | United States | 33.94 | -82.12 | 830 | |
| Maysville | city | South Carolina | United States | 34.81 | -80.17 | 291 |