| Name | What | Region | Country | Lat | Long | Elev ft. | Pop est |
|---|---|---|---|---|---|---|---|
| Lobeco | city | South Carolina | United States | 32.55 | -80.74 | 3 | |
| Loblolly Pines | city | South Carolina | United States | 34.51 | -82.70 | 830 | |
| Lockhart | city | South Carolina | United States | 34.79 | -81.46 | 387 | |
| Lockhart Junction | city | South Carolina | United States | 34.82 | -81.65 | 830 | |
| Lockhart Oil Field | city | South Carolina | United States | 34.42 | -80.53 | 830 | |
| Locklair (historical) | city | South Carolina | United States | 33.15 | -80.04 | 49 | |
| Locksley Hall | city | South Carolina | United States | 34.23 | -82.20 | 830 | |
| Lockwood Hall | city | South Carolina | United States | 32.73 | -79.92 | 3 | |
| Lockwood Heights | city | South Carolina | United States | 34.85 | -82.45 | 1013 | |
| Locust Hill | city | South Carolina | United States | 35.02 | -82.38 | 1095 | |
| Locust Tree Landing | city | South Carolina | United States | 33.96 | -79.33 | 22 | |
| Lodge | city | South Carolina | United States | 33.07 | -80.95 | 108 | |
| Lodge Grounds | city | South Carolina | United States | 34.19 | -82.18 | 830 | |
| Lodge Hall | city | South Carolina | United States | 33.33 | -79.47 | 36 | |
| Log Jam Landing | city | South Carolina | United States | 33.52 | -80.30 | 68 | |
| Log Town (historical) | city | South Carolina | United States | 34.26 | -80.60 | 180 | |
| Lone Oak | city | South Carolina | United States | 34.99 | -81.98 | 898 | |
| Lone Oak Estates | city | South Carolina | United States | 34.47 | -82.61 | 830 | |
| Lone Star | city | South Carolina | United States | 33.63 | -80.59 | 150 | |
| Long Bay | city | South Carolina | United States | 33.75 | -78.81 | 13 | |
| Long Bay Estates | city | South Carolina | United States | 33.64 | -78.94 | 0 | |
| Long Bottom Ford | city | South Carolina | United States | 34.90 | -83.19 | 1833 | |
| Long Branch | city | South Carolina | United States | 34.51 | -81.90 | 830 | |
| Long Branch | city | South Carolina | United States | 33.32 | -81.39 | 262 | |
| Long Branch Estates | city | South Carolina | United States | 32.80 | -80.05 | 9 | |
| Long Cane (historical) | city | South Carolina | United States | 34.15 | -82.33 | 830 | |
| Long Cove Plantation | city | South Carolina | United States | 32.17 | -80.75 | 9 | |
| Long Creek Landing | city | South Carolina | United States | 32.94 | -80.40 | 29 | |
| Long Meadows | city | South Carolina | United States | 34.53 | -82.61 | 830 | |
| Long Point | city | South Carolina | United States | 34.02 | -78.88 | 98 | |
| Long Ridge | city | South Carolina | United States | 33.14 | -80.16 | 68 | |
| Longcreek | city | South Carolina | United States | 34.77 | -83.26 | 1669 | |
| Longcreek | city | South Carolina | United States | 34.84 | -82.55 | 892 | |
| Longleaf | city | South Carolina | United States | 34.15 | -79.78 | 118 | |
| Longleaf | city | South Carolina | United States | 33.62 | -78.99 | 26 | |
| Longs | city | South Carolina | United States | 33.94 | -78.73 | 26 | |
| Longshore | city | South Carolina | United States | 34.27 | -81.75 | 830 | |
| Longtown | city | South Carolina | United States | 34.35 | -80.84 | 830 | |
| Longview Plant | city | South Carolina | United States | 34.02 | -81.39 | 400 | |
| Longwood | city | South Carolina | United States | 33.81 | -79.08 | 16 | |
| Longwood | city | South Carolina | United States | 32.32 | -80.61 | 3 | |
| Longwood Landing | city | South Carolina | United States | 33.61 | -79.09 | 19 | |
| Lopers Crossroads | city | South Carolina | United States | 32.93 | -81.27 | 98 | |
| Loraine (historical) | city | South Carolina | United States | 33.35 | -81.08 | 229 | |
| Loran Point | city | South Carolina | United States | 34.71 | -82.95 | 830 | |
| Lorena Park | city | South Carolina | United States | 34.91 | -82.31 | 918 | |
| Lorenzo (historical) | city | South Carolina | United States | 34.15 | -82.24 | 830 | |
| Loris | city | South Carolina | United States | 34.06 | -78.89 | 104 | |
| Lost Creek | city | South Carolina | United States | 34.11 | -81.14 | 259 | |
| Lota | city | South Carolina | United States | 34.25 | -82.05 | 830 | |
| Lotts Crossroads | city | South Carolina | United States | 33.04 | -80.25 | 59 | |
| Love Springs | city | South Carolina | United States | 35.05 | -81.77 | 830 | |
| Lower Topsaw Landing | city | South Carolina | United States | 33.61 | -79.15 | 9 | |
| Lowmans Crossroads (historical) | city | South Carolina | United States | 34.11 | -81.49 | 387 | |
| Lowndes Landing | city | South Carolina | United States | 32.87 | -80.40 | 9 | |
| Lowndesville | city | South Carolina | United States | 34.21 | -82.65 | 830 | |
| Lowrys | city | South Carolina | United States | 34.80 | -81.24 | 830 |