| Name | What | Region | Country | Lat | Long | Elev ft. | Pop est |
|---|---|---|---|---|---|---|---|
| Leaphart | city | South Carolina | United States | 34.05 | -81.15 | 200 | |
| Leavensworth (historical) | city | South Carolina | United States | 34.41 | -79.94 | 98 | |
| Leawood | city | South Carolina | United States | 34.89 | -82.40 | 1000 | |
| Leawood | city | South Carolina | United States | 33.89 | -80.31 | 141 | |
| Lebanon | city | South Carolina | United States | 34.62 | -82.69 | 830 | |
| Lebanon | city | South Carolina | United States | 33.14 | -80.21 | 75 | |
| Lebanon | city | South Carolina | United States | 34.41 | -81.20 | 830 | |
| Lee Acres | city | South Carolina | United States | 34.17 | -79.81 | 118 | |
| Lee Crossroads | city | South Carolina | United States | 33.87 | -79.67 | 62 | |
| Lee Hills | city | South Carolina | United States | 33.98 | -80.89 | 275 | |
| Lee Jackson Estates | city | South Carolina | United States | 32.73 | -79.97 | 13 | |
| Leeds | city | South Carolina | United States | 34.63 | -81.40 | 396 | |
| Lees | city | South Carolina | United States | 33.35 | -81.21 | 249 | |
| Lees Crossroads | city | South Carolina | United States | 34.73 | -80.19 | 403 | |
| Lees Crossroads | city | South Carolina | United States | 34.30 | -80.09 | 196 | |
| Leesburg | city | South Carolina | United States | 34.02 | -80.71 | 200 | |
| Leesville | city | South Carolina | United States | 33.92 | -81.51 | 830 | |
| Leeward Landing | city | South Carolina | United States | 34.57 | -82.72 | 830 | |
| Legare (historical) | city | South Carolina | United States | 33.28 | -80.23 | 91 | |
| Legareville | city | South Carolina | United States | 32.65 | -80.05 | 9 | |
| Leigh (historical) | city | South Carolina | United States | 33.20 | -81.72 | 137 | |
| Leisure Village | city | South Carolina | United States | 34.55 | -82.80 | 830 | |
| Leland | city | South Carolina | United States | 34.44 | -80.17 | 301 | |
| Lena | city | South Carolina | United States | 32.75 | -81.22 | 108 | |
| Lendaw | city | South Carolina | United States | 35.05 | -82.31 | 1013 | |
| Lenoir (historical) | city | South Carolina | United States | 33.60 | -82.02 | 298 | |
| Leo | city | South Carolina | United States | 33.83 | -79.62 | 49 | |
| Leslie Woods | city | South Carolina | United States | 34.90 | -80.93 | 830 | |
| Lesslie | city | South Carolina | United States | 34.89 | -80.96 | 830 | |
| Lester | city | South Carolina | United States | 34.68 | -79.65 | 177 | |
| Lethia | city | South Carolina | United States | 33.97 | -82.41 | 830 | |
| Level Land | city | South Carolina | United States | 34.33 | -82.48 | 830 | |
| Lever (historical) | city | South Carolina | United States | 34.20 | -81.11 | 252 | |
| Levy | city | South Carolina | United States | 32.20 | -81.03 | 3 | |
| Lewis | city | South Carolina | United States | 34.78 | -81.13 | 830 | |
| Lewis Crossroads | city | South Carolina | United States | 34.33 | -79.97 | 200 | |
| Lewisville (historical) | city | South Carolina | United States | 34.74 | -81.03 | 830 | |
| Lewisville (historical) | city | South Carolina | United States | 34.03 | -79.08 | 108 | |
| Lexing-Town Estates | city | South Carolina | United States | 33.96 | -81.28 | 400 | |
| Lexington | city | South Carolina | United States | 33.98 | -81.24 | 298 | |
| Lexington Place | city | South Carolina | United States | 34.56 | -82.70 | 830 | |
| Lexington Woods | city | South Carolina | United States | 33.98 | -81.24 | 308 |