| Name | What | Region | Country | Lat | Long | Elev ft. | Pop est |
|---|---|---|---|---|---|---|---|
| Sobrino | city | Puerto Rico | United States | 18.34 | -66.32 | 830 | |
| Sol y Mar | city | Puerto Rico | United States | 18.49 | -67.01 | 321 | |
| Solimar | city | Puerto Rico | United States | 18.38 | -65.72 | 3 | |
| Soroco | city | Puerto Rico | United States | 18.37 | -65.63 | 0 | |
| Sosa | city | Puerto Rico | United States | 18.02 | -67.16 | 45 |