| Name | What | Region | Country | Lat | Long | Elev ft. | Pop est |
|---|---|---|---|---|---|---|---|
| Cuarta de Tierra | city | Puerto Rico | United States | 18.01 | -66.54 | 32 | |
| Cuatro Calles | city | Puerto Rico | United States | 18.01 | -66.60 | 65 | |
| Cuatro Calles | city | Puerto Rico | United States | 18.43 | -66.80 | 830 | |
| Cuatro Calles | city | Puerto Rico | United States | 18.03 | -67.14 | 39 | |
| Cuatro Calles | city | Puerto Rico | United States | 18.04 | -66.46 | 830 | |
| Cuatro Calles (historical) | city | Puerto Rico | United States | 18.49 | -67.12 | 226 | |
| Cuatro Caminos | city | Puerto Rico | United States | 18.05 | -67.15 | 190 | |
| Cuba | city | Puerto Rico | United States | 18.39 | -67.10 | 157 | |
| Cucharillas | city | Puerto Rico | United States | 18.44 | -66.15 | 9 | |
| Cuebas | city | Puerto Rico | United States | 18.05 | -66.71 | 830 | |
| Cuebas | city | Puerto Rico | United States | 18.20 | -67.13 | 239 | |
| Cuesta de las Piedras | city | Puerto Rico | United States | 18.18 | -67.14 | 209 | |
| Culebra | city | Puerto Rico | United States | 18.30 | -65.30 | 52 | |
| Culebra Zona Urbana | city | Puerto Rico | United States | 18.31 | -65.30 | 3 | |
| Cupey Gardens | city | Puerto Rico | United States | 18.36 | -66.05 | 321 |