| Name | What | Region | Country | Lat | Long | Elev ft. | Pop est |
|---|---|---|---|---|---|---|---|
| Spang Mills | city | Maine | United States | 43.48 | -70.64 | 200 | |
| Spaulding | city | Maine | United States | 46.88 | -68.24 | 830 | |
| Spears Corner | city | Maine | United States | 44.20 | -69.88 | 219 | |
| Split Hill | city | Maine | United States | 44.83 | -67.04 | 131 | |
| Spooners Mill | city | Maine | United States | 45.01 | -69.27 | 393 | |
| Sprague City | city | Maine | United States | 43.63 | -70.84 | 830 | |
| Sprague Corner | city | Maine | United States | 44.07 | -69.44 | 147 | |
| Sprague Mill | city | Maine | United States | 44.19 | -70.12 | 298 | |
| Spragues Mill | city | Maine | United States | 44.91 | -69.25 | 249 | |
| Spragueville | city | Maine | United States | 46.63 | -68.01 | 830 | |
| Spring Lake | city | Maine | United States | 45.23 | -70.28 | 1669 | |
| Spring Lake Landing | city | Maine | United States | 45.25 | -70.22 | 1099 | |
| Springfield | city | Maine | United States | 45.40 | -68.14 | 830 | |
| Springvale | city | Maine | United States | 43.47 | -70.79 | 334 | |
| Spruce Head | city | Maine | United States | 44.01 | -69.13 | 0 | |
| Spruce Shores | city | Maine | United States | 43.83 | -69.60 | 16 | |
| Spruceworld | city | Maine | United States | 43.84 | -69.62 | 3 | |
| Spurrs Corner | city | Maine | United States | 44.06 | -70.56 | 830 |