| Name | What | Region | Country | Lat | Long | Elev ft. | Pop est |
|---|---|---|---|---|---|---|---|
| Sabaleta de en Medio | city | Esmeraldas | Ecuador | 0.35 | -79.62 | 1020 | 3323 |
| Sade | city | Esmeraldas | Ecuador | 0.51 | -79.38 | 830 | 2049 |
| Salima | city | Esmeraldas | Ecuador | 0.32 | -79.97 | 393 | 4582 |
| Same | city | Esmeraldas | Ecuador | 0.85 | -79.93 | 9 | 7898 |
| San Agustin | city | Esmeraldas | Ecuador | 0.99 | -79.02 | 183 | 5180 |
| San Agustín | city | Esmeraldas | Ecuador | 1.04 | -78.92 | 206 | 2935 |
| San Agustín de Cayapas | city | Esmeraldas | Ecuador | 0.99 | -79.02 | 183 | 5180 |
| San Antonio | city | Esmeraldas | Ecuador | 0.95 | -78.65 | 1669 | 1109 |
| San Antonio | city | Esmeraldas | Ecuador | 1.30 | -78.79 | 75 | 1013 |
| San Carlos de Calope | city | Esmeraldas | Ecuador | 1.00 | -79.50 | 830 | 1691 |
| San Enrique | city | Esmeraldas | Ecuador | 0.72 | -79.85 | 869 | 868 |
| San Francisco | city | Esmeraldas | Ecuador | 0.89 | -79.08 | 321 | 953 |
| San Francisco | city | Esmeraldas | Ecuador | 1.09 | -78.70 | 938 | 1537 |
| San Francisco | city | Esmeraldas | Ecuador | 0.77 | -80.05 | 1020 | 3166 |
| San Francisco | city | Esmeraldas | Ecuador | 1.25 | -78.90 | 3 | 9360 |
| San Francisco de Onzole | city | Esmeraldas | Ecuador | 1.09 | -78.70 | 938 | 1537 |
| San Francisco de Onzole | city | Esmeraldas | Ecuador | 0.89 | -79.08 | 321 | 953 |
| San Gregorio | city | Esmeraldas | Ecuador | 0.53 | -79.97 | 305 | 2612 |
| San Isidro | city | Esmeraldas | Ecuador | 0.12 | -79.53 | 830 | 2812 |
| San Jacinto del Chipo | city | Esmeraldas | Ecuador | 0.30 | -79.38 | 830 | 8111 |
| San Javier | city | Esmeraldas | Ecuador | 1.07 | -78.78 | 830 | 1633 |
| San Javier de Cachabí | city | Esmeraldas | Ecuador | 1.07 | -78.78 | 830 | 1633 |
| San Javier de Cachavi | city | Esmeraldas | Ecuador | 1.07 | -78.78 | 830 | 1633 |
| San Jose de Chamanga | city | Esmeraldas | Ecuador | 0.27 | -79.94 | 406 | 2371 |
| San Jose de Tagua | city | Esmeraldas | Ecuador | 1.01 | -78.83 | 347 | 2114 |
| San José | city | Esmeraldas | Ecuador | 0.97 | -78.70 | 1158 | 1202 |
| San José de Cayapas | city | Esmeraldas | Ecuador | 0.97 | -79.02 | 213 | 4272 |
| San Lorenzo | city | Esmeraldas | Ecuador | 1.29 | -78.84 | 3 | 9094 |
| San Lorenzo de Esmeraldas | city | Esmeraldas | Ecuador | 1.29 | -78.84 | 3 | 9094 |
| San Mateo | city | Esmeraldas | Ecuador | 0.89 | -79.63 | 59 | 10784 |
| San Miguel | city | Esmeraldas | Ecuador | 0.74 | -78.92 | 830 | 313 |
| San Miguel de Cayapas | city | Esmeraldas | Ecuador | 0.74 | -78.92 | 830 | 313 |
| San Miguel de Guabal | city | Esmeraldas | Ecuador | -0.06 | -79.58 | 830 | 537 |
| San Pedro | city | Esmeraldas | Ecuador | 1.38 | -78.89 | 3 | 13996 |
| San Rafael | city | Esmeraldas | Ecuador | 1.07 | -78.83 | 275 | 1855 |
| San Ramón | city | Esmeraldas | Ecuador | 0.30 | -79.57 | 830 | 3576 |
| San Roque | city | Esmeraldas | Ecuador | 0.15 | -79.54 | 830 | 3584 |
| San Roque Arenanga | city | Esmeraldas | Ecuador | 0.28 | -79.55 | 830 | 3576 |
| San Vicente | city | Esmeraldas | Ecuador | 0.82 | -79.83 | 830 | 10814 |
| San Xavier | city | Esmeraldas | Ecuador | 1.07 | -78.78 | 830 | 1633 |
| Santa Rita | city | Esmeraldas | Ecuador | 1.10 | -78.73 | 830 | 1691 |
| Santa Rosa | city | Esmeraldas | Ecuador | 1.33 | -78.94 | 3 | 26649 |
| Santiago Playa de Oro | city | Esmeraldas | Ecuador | 0.88 | -78.79 | 830 | 546 |
| Sapallo Grande | city | Esmeraldas | Ecuador | 0.78 | -78.98 | 830 | 604 |
| Sapayo Grande | city | Esmeraldas | Ecuador | 0.78 | -78.98 | 830 | 604 |
| Selva Alegre | city | Esmeraldas | Ecuador | 0.93 | -78.86 | 830 | 2396 |
| Shumunde | city | Esmeraldas | Ecuador | 0.83 | -79.42 | 370 | 1586 |
| Silencio Grande | city | Esmeraldas | Ecuador | 0.14 | -79.36 | 830 | 4353 |
| Simón Bolívar | city | Esmeraldas | Ecuador | 0.30 | -79.27 | 830 | 3353 |
| Sua | city | Esmeraldas | Ecuador | 0.86 | -79.87 | 0 | 11583 |
| Sucre | city | Esmeraldas | Ecuador | 1.00 | -78.80 | 830 | 1607 |