| Name | What | Region | Country | Lat | Long | Elev ft. | Pop est |
|---|---|---|---|---|---|---|---|
| DZO (SANTA BERNARDINA INTL) | airport | Uruguay | -33.36 | -56.50 | 305 | 0 | |
| Darwin | city | Soriano | Uruguay | -33.11 | -57.63 | 114 | 294 |
| Daymán | city | Paysandu | Uruguay | -31.53 | -57.90 | 173 | 195 |
| De los Pastores | city | Lavalleja | Uruguay | -33.17 | -54.97 | 830 | 149 |
| Delta del Tigre | city | San Jose | Uruguay | -34.76 | -56.39 | 82 | 63100 |
| Diecinueve de Abril | city | Rocha | Uruguay | -34.36 | -54.07 | 6 | 149 |
| Diecinueve de Junio | city | Rocha | Uruguay | -33.61 | -54.33 | 32 | 149 |
| Dieciocho de Julio | city | San Jose | Uruguay | -34.44 | -56.44 | 118 | 11075 |
| Dieciocho de Julio | city | Rocha | Uruguay | -33.68 | -53.55 | 236 | 745 |
| Diego Lamas | city | Artigas | Uruguay | -30.75 | -57.06 | 830 | 298 |
| Diez y Ocho de Julio | city | Rocha | Uruguay | -33.68 | -53.55 | 236 | 745 |
| Doctor Francisco Soca | city | Canelones | Uruguay | -34.68 | -55.70 | 49 | 7220 |
| Doctor Soca | city | Canelones | Uruguay | -34.68 | -55.70 | 49 | 7220 |
| Dolores | city | Soriano | Uruguay | -33.53 | -58.22 | 91 | 12316 |
| Doloresas | city | Soriano | Uruguay | -33.53 | -58.22 | 91 | 12316 |
| Don Carlos Chico | city | Rocha | Uruguay | -34.34 | -54.23 | 318 | 149 |
| Don Esteban | city | Rio Negro | Uruguay | -32.61 | -57.36 | 278 | 1987 |
| Drabble | city | Soriano | Uruguay | -33.70 | -57.53 | 830 | 4601 |
| Drable | city | Soriano | Uruguay | -33.70 | -57.53 | 830 | 4601 |
| Duranzo | city | Durazno | Uruguay | -33.38 | -56.52 | 285 | 26126 |
| Durasnas | city | Durazno | Uruguay | -33.38 | -56.52 | 285 | 26126 |
| Duraznito | city | Soriano | Uruguay | -33.63 | -57.44 | 328 | 298 |
| Duraznito | city | Soriano | Uruguay | -33.65 | -57.53 | 406 | 2932 |
| Durazno | city | Durazno | Uruguay | -33.38 | -56.52 | 285 | 26126 |
| Díaz | city | Lavalleja | Uruguay | -33.13 | -54.93 | 830 | 149 |