| Name | What | Region | Country | Lat | Long | Elev ft. | Pop est |
|---|---|---|---|---|---|---|---|
| Spruance City | city | Delaware | United States | 39.29 | -75.62 | 19 | |
| Spruce | city | Colorado | United States | 39.16 | -104.88 | 7549 | |
| Spruce | city | Minnesota | United States | 47.43 | -92.56 | 1669 | |
| Spruce | city | Missouri | United States | 38.27 | -94.13 | 830 | |
| Spruce | city | Nevada | United States | 40.80 | -114.66 | 5869 | |
| Spruce | city | Pennsylvania | United States | 40.68 | -78.86 | 1784 | |
| Spruce | city | Pennsylvania | United States | 41.15 | -78.00 | 882 | |
| Spruce | city | West Virginia | United States | 38.46 | -79.96 | 4189 | |
| Spruce | city | Wisconsin | United States | 44.95 | -88.16 | 830 | |
| Spruce | city | Michigan | United States | 45.99 | -87.78 | 1105 | |
| Spruce | city | Michigan | United States | 44.84 | -83.47 | 892 | |
| Spruce (historical) | city | California | United States | 39.32 | -120.43 | 6709 | |
| Spruce Center | city | Minnesota | United States | 46.07 | -95.22 | 1669 | |
| Spruce Corner | city | Massachusetts | United States | 42.50 | -72.85 | 1669 | |
| Spruce Corner (historical) | city | Connecticut | United States | 41.33 | -72.59 | 124 | |
| Spruce Creek | city | Pennsylvania | United States | 40.61 | -78.14 | 830 | |
| Spruce Gardens | city | New Jersey | United States | 40.07 | -74.21 | 91 | |
| Spruce Grove | city | Pennsylvania | United States | 39.81 | -76.07 | 377 | |
| Spruce Head | city | Maine | United States | 44.01 | -69.13 | 0 | |
| Spruce Hill | city | Pennsylvania | United States | 40.48 | -77.45 | 830 | |
| Spruce Hill | city | Pennsylvania | United States | 39.95 | -75.22 | 72 | |
| Spruce Hill | city | Pennsylvania | United States | 41.20 | -75.23 | 1669 | |
| Spruce Hill | city | Maryland | United States | 38.36 | -76.47 | 3 | |
| Spruce Hill | city | Virginia | United States | 37.37 | -80.03 | 1669 | |
| Spruce Hill Estates | city | Maryland | United States | 39.06 | -76.65 | 144 | |
| Spruce Pine | city | Alabama | United States | 34.39 | -87.73 | 1000 | |
| Spruce Pine | city | Kentucky | United States | 36.92 | -83.45 | 1879 | |
| Spruce Pine | city | North Carolina | United States | 35.92 | -82.06 | 2565 | |
| Spruce Pine | city | Tennessee | United States | 36.39 | -83.21 | 1204 | |
| Spruce Point | city | California | United States | 40.74 | -124.20 | 134 | |
| Spruce Run | city | New Jersey | United States | 40.71 | -74.92 | 830 | |
| Spruce Shadows Mobile Home Park | city | Minnesota | United States | 47.49 | -92.89 | 1669 | |
| Spruce Shores | city | Maine | United States | 43.83 | -69.60 | 16 | |
| Spruce Tree Village | city | Ohio | United States | 40.87 | -81.92 | 1095 | |
| Spruce Valley | city | West Virginia | United States | 37.88 | -81.82 | 1669 | |
| Spruce West Mobile Home Park | city | Washington | United States | 48.08 | -123.12 | 209 | |
| Sprucedale | city | Arizona | United States | 33.74 | -109.33 | 7598 | |
| Sprucedale | city | Colorado | United States | 39.59 | -105.35 | 7644 | |
| Sprucemont | city | Nevada | United States | 40.55 | -114.87 | 7020 | |
| Spruces | city | Pennsylvania | United States | 39.96 | -75.82 | 830 | |
| Spruceton | city | New York | United States | 42.19 | -74.31 | 2047 | |
| Sprucetown | city | Pennsylvania | United States | 39.75 | -79.91 | 830 | |
| Sprucetree Mobile Home Court | city | Michigan | United States | 42.28 | -84.94 | 948 | |
| Sprucevale | city | Ohio | United States | 40.71 | -80.58 | 951 | |
| Sprucewood | city | Colorado | United States | 39.35 | -105.12 | 7549 | |
| Sprucewood | city | South Carolina | United States | 32.95 | -80.22 | 9 | |
| Sprucewood | city | Utah | United States | 40.56 | -111.86 | 4596 | |
| Spruceworld | city | Maine | United States | 43.84 | -69.62 | 3 | |
| Sprudel | city | Arkansas | United States | 33.62 | -93.77 | 249 | |
| Sprule | city | Kentucky | United States | 37.02 | -83.85 | 1040 |