| Name | What | Region | Country | Lat | Long | Elev ft. | Pop est |
|---|---|---|---|---|---|---|---|
| Meador (historical) | city | South Carolina | United States | 34.69 | -81.51 | 400 | |
| Meadow Brook | city | South Carolina | United States | 34.26 | -79.78 | 111 | |
| Meadow Brook | city | South Carolina | United States | 34.68 | -82.81 | 830 | |
| Meadow Brook | city | South Carolina | United States | 34.49 | -82.57 | 830 | |
| Meadow Fields | city | South Carolina | United States | 34.44 | -82.64 | 830 | |
| Meadow Lake | city | South Carolina | United States | 34.08 | -81.00 | 298 | |
| Meadow Lakes | city | South Carolina | United States | 34.94 | -81.08 | 830 | |
| Meadow Oaks | city | South Carolina | United States | 34.33 | -80.10 | 206 | |
| Meadow Park | city | South Carolina | United States | 34.46 | -82.65 | 830 | |
| Meadow Rose | city | South Carolina | United States | 34.68 | -82.81 | 830 | |
| Meadow Spring | city | South Carolina | United States | 35.01 | -81.92 | 879 | |
| Meadow View | city | South Carolina | United States | 34.12 | -80.71 | 170 | |
| Meadowbrook | city | South Carolina | United States | 33.02 | -80.16 | 75 | |
| Meadowbrook Farms | city | South Carolina | United States | 35.04 | -82.03 | 830 | |
| Meadowbrook Heights | city | South Carolina | United States | 34.52 | -82.70 | 830 | |
| Meadowfield | city | South Carolina | United States | 33.96 | -80.96 | 180 | |
| Meadowridge | city | South Carolina | United States | 33.52 | -80.91 | 209 | |
| Mealing Heights | city | South Carolina | United States | 33.49 | -81.96 | 187 | |
| Mean Crossroads | city | South Carolina | United States | 34.81 | -81.73 | 830 | |
| Meansville (historical) | city | South Carolina | United States | 34.81 | -81.75 | 830 | |
| Mechanicsville | city | South Carolina | United States | 34.34 | -79.76 | 134 | |
| Mechanicsville | city | South Carolina | United States | 34.10 | -80.32 | 170 | |
| Meeks | city | South Carolina | United States | 34.20 | -79.71 | 118 | |
| Meeting Street | city | South Carolina | United States | 33.94 | -81.93 | 830 | |
| Meggett | city | South Carolina | United States | 32.72 | -80.24 | 3 | |
| Melbourne Heights | city | South Carolina | United States | 34.52 | -82.64 | 830 | |
| Melgrove (historical) | city | South Carolina | United States | 32.93 | -79.99 | 3 | |
| Melrose | city | South Carolina | United States | 32.79 | -80.05 | 9 | |
| Melrose Heights | city | South Carolina | United States | 34.01 | -81.00 | 298 | |
| Melwood | city | South Carolina | United States | 33.95 | -81.18 | 311 | |
| Menriv Park | city | South Carolina | United States | 32.97 | -79.98 | 32 | |
| Mepkin | city | South Carolina | United States | 33.11 | -79.95 | 22 | |
| Mercer (historical) | city | South Carolina | United States | 35.02 | -81.54 | 830 | |
| Merchant (historical) | city | South Carolina | United States | 34.04 | -81.67 | 406 | |
| Merchant Estates | city | South Carolina | United States | 34.81 | -82.36 | 928 | |
| Meriwether | city | South Carolina | United States | 33.65 | -82.16 | 383 | |
| Merrifield Park | city | South Carolina | United States | 34.86 | -82.31 | 964 | |
| Merritts Bridge (historical) | city | South Carolina | United States | 33.69 | -81.59 | 830 | |
| Merrittsville (historical) | city | South Carolina | United States | 35.15 | -82.41 | 1230 | |
| Metz Store (historical) | city | South Carolina | United States | 32.99 | -80.49 | 59 | |
| Mexico | city | South Carolina | United States | 34.94 | -81.00 | 830 |