| Name | What | Region | Country | Lat | Long | Elev ft. | Pop est |
|---|---|---|---|---|---|---|---|
| Escambia (historical) | city | Florida | United States | 30.05 | -85.05 | 22 | |
| Escambia Farms | city | Florida | United States | 30.96 | -86.63 | 206 | |
| Esco Park | city | Florida | United States | 28.00 | -82.40 | 45 | |
| Espanola | city | Florida | United States | 29.51 | -81.31 | 22 | |
| Essex Downs | city | Florida | United States | 28.00 | -82.59 | 6 | |
| Estanifanulga (historical) | city | Florida | United States | 30.17 | -85.13 | 16 | |
| Estates at Limona Woods | city | Florida | United States | 27.95 | -82.30 | 45 | |
| Estates at Parsons Pointe | city | Florida | United States | 28.00 | -82.29 | 72 | |
| Estates del Sol | city | Florida | United States | 27.82 | -82.32 | 78 | |
| Estates of Lake Alice | city | Florida | United States | 28.13 | -82.61 | 36 | |
| Estates of Rock Lake | city | Florida | United States | 28.12 | -82.56 | 39 | |
| Estelle Estates | city | Florida | United States | 28.02 | -82.48 | 26 | |
| Estelle's Mobile Home Park | city | Florida | United States | 30.30 | -81.78 | 22 | |
| Estero | city | Florida | United States | 26.44 | -81.81 | 6 | |
| Estiffanulga | city | Florida | United States | 30.31 | -85.03 | 49 | |
| Esto | city | Florida | United States | 30.99 | -85.65 | 200 | |
| Estuary | city | Florida | United States | 27.95 | -82.45 | 3 |