| Name | What | Region | Country | Lat | Long | Elev ft. | Pop est |
|---|---|---|---|---|---|---|---|
| The Sands | city | Mpumalanga | South Africa | -25.23 | 31.08 | 2509 | 25060 |
| The Sentinels | city | North West | South Africa | -26.62 | 27.08 | 4478 | 1809 |
| The Shadows | city | Eastern Cape | South Africa | -33.85 | 25.32 | 830 | 6896 |
| The Shawe | city | KwaZulu-Natal | South Africa | -28.66 | 29.97 | 3631 | 10810 |
| The Shelter | city | KwaZulu-Natal | South Africa | -29.71 | 29.69 | 5029 | 2034 |
| The Shelter | city | Limpopo | South Africa | -24.47 | 30.17 | 3349 | 21142 |
| The Shiloh Mission Station | city | Eastern Cape | South Africa | -32.20 | 26.83 | 3543 | 36227 |
| The Shoot | city | Mpumalanga | South Africa | -25.74 | 30.81 | 3349 | 2773 |
| The Side | city | KwaZulu-Natal | South Africa | -30.20 | 29.35 | 5045 | 568 |
| The Slab | city | Limpopo | South Africa | -23.67 | 30.99 | 1082 | 139 |
| The Smugglers Union | city | Limpopo | South Africa | -24.55 | 29.43 | 2828 | 18721 |
| The Spinnies | city | KwaZulu-Natal | South Africa | -28.63 | 30.89 | 4189 | 6260 |
| The Spring | city | KwaZulu-Natal | South Africa | -28.76 | 30.26 | 2582 | 6571 |
| The Springs | city | Eastern Cape | South Africa | -33.70 | 25.44 | 830 | 17579 |
| The Springs | city | Western Cape | South Africa | -34.64 | 19.71 | 830 | 145 |
| The Springs | city | KwaZulu-Natal | South Africa | -30.26 | 29.09 | 5029 | 307 |
| The Sprip | city | KwaZulu-Natal | South Africa | -28.35 | 30.12 | 4189 | 1581 |
| The Star | city | Eastern Cape | South Africa | -32.84 | 23.53 | 2509 | 0 |
| The Strath | city | Eastern Cape | South Africa | -32.47 | 27.65 | 2509 | 2242 |
| The Strip | city | KwaZulu-Natal | South Africa | -28.33 | 29.79 | 5249 | 5977 |
| The Strip | city | Mpumalanga | South Africa | -25.87 | 30.75 | 5029 | 428 |
| The Summit Farm | city | Limpopo | South Africa | -23.73 | 30.07 | 3704 | 1863 |