| Name | What | Region | Country | Lat | Long | Elev ft. | Pop est |
|---|---|---|---|---|---|---|---|
| Sebastián | city | Santiago de Cuba | Cuba | 20.13 | -76.18 | 1669 | 5221 |
| SebastÃan | city | Santiago de Cuba | Cuba | 20.17 | -75.75 | 830 | 35374 |
| Seboruco | city | Santiago de Cuba | Cuba | 20.34 | -75.57 | 1669 | 6258 |
| Seboruco | city | Santiago de Cuba | Cuba | 20.32 | -75.59 | 1158 | 4444 |
| Segrego Almeida | city | Santiago de Cuba | Cuba | 20.50 | -75.98 | 314 | 3427 |
| Segrego Bucuey | city | Santiago de Cuba | Cuba | 20.27 | -75.77 | 830 | 5737 |
| Segrego de Vaillant | city | Santiago de Cuba | Cuba | 20.32 | -75.58 | 1190 | 4497 |
| Segregos de Bucuey | city | Santiago de Cuba | Cuba | 20.27 | -75.77 | 830 | 5737 |
| Segregos de Palmar y el Coco | city | Santiago de Cuba | Cuba | 19.92 | -75.55 | 387 | 11872 |
| Segura | city | Santiago de Cuba | Cuba | 20.26 | -76.11 | 830 | 3427 |
| Serafina | city | Santiago de Cuba | Cuba | 20.10 | -76.05 | 954 | 6492 |
| Serres | city | Santiago de Cuba | Cuba | 19.93 | -75.62 | 830 | 9683 |
| Sevilla | city | Santiago de Cuba | Cuba | 20.01 | -75.73 | 393 | 81752 |
| Sevilla | city | Santiago de Cuba | Cuba | 19.97 | -76.35 | 0 | 2427 |